SALBUTAMOL

mechanism of Action

It has a potent selective b2 stimulant action on bronchial muscles causing bronchodilation and very less b1 or cardiac stimulant action and hence safer than non selective b stimulants. It has a longer duration of action as compared to non selective agonists like adrenaline etc. because it is resistant to inactivation by COMT

 

Indications

Acute asthma attacks and its prophylaxis

 

Dosage 

Adults: 2 - 4mg three times daily (available as 2 and 4mg tablets) or 200-400mcg (1-2 puff or 1 rota cap)

(Available as 200mcg/ puff inhaler and 400mcg rota cap)

Children: 1 - 2mg three times daily (available as 2mg/5ml syrup) or 200mcg (1puff inhaler)

Or nebulisation giving 2.5mg in 1 nebulisation

 

Adverse Drug Reactions

Relatively very safe

 

Status in

1. Pregnancy : Safe

2. Lactation : Safe

3. Old age : Safe

4. Infants : Safe

 

 

Brands available and preparation of SALBUTAMOL

 

Pharmaceutical Company

Brand Name

Aristo

 

AMBRODIL-S (Salbutamol 1mg, Ambroxol HCl 15mg, per 5ml)

   100ml syr                

Tablets India

AMBROLITE-S  (Salbutamol 1mg, Ambroxol HCl 30mg, Guaiaphenesin 50mg/5ml)

   100ml Syr.     

 

AMBROLITE-2S (Salbutamol 2mg, Ambroxol HCl 30mg,  Guaiaphenesin 50mg/5ml)

   100ml Syr.

 

Chemech Labs

AMBSOL   (Salbutamol 1mg, Ambroxol HCl 30mg, Guaiaphenesin 50mg/5ml)

   100ml Syr.  

 

Inga

ASMANIL                              

   10 Tab                    2mg   

                               4mg   

 

Cipla

ASTHALIN                           

   10 Tab                    2mg  

                                4mg    

   10 TabSA               4mg    

                                8mg   

   100ml Syr         2mg/5ml   

 

MUCOLINC EXP. (Salbutamol 2mg, bromhexine HCl 4mg, per 5ml)

   100ml Syr.    

 

MUCOLINC TAB   (Salbutamol 1mg, bromhexine Hcl 8mg)

   10 Tab    

 

GSK

BRONKOTAB EX   (Salbutamol 2mg, bromhexine HCl 4mg)

   10 Tab   

 

BRONKOTAB 4 EX.  (Salbutamol 4mg, bromhexine HCl 4mg)          

   10 Tab             

 

VENTORLIN  

   100ml Syr         2mg/5ml   

   10 Cap CR              4mg   

8mg  

 

Indo French

BRONMIX                    

Tab : Salbutamol 2mg, Guaiaphenesin 200mg, bromhexine 2mg, per 5ml)

   100ml Syr

 

Syr.  Salbutamol 1mg, Guaiaphenesin 50mg, bromhexine 2mg, per 5ml)

   100ml Syr.

 

Lark Labs

BROSOL                      

   10 Tab                    2mg  

                                4mg   

 

Wander

CORIMINIC X                

(Salbutamol sulphate 1mg, Ambroxol HCl 30mg, Guaiaphenesin 50mg, menthol 0.5mg, per 5ml)

   100ml Liq.    

 

Raptakos

DURASAL-CR   (Salbutamol controlled release)

   10 Cap SR              4mg      

                                8mg    

 

Cachet

EASCOF                           

(Salbutamol 2mg, bromhexine Hcl 4mg, Guaiaphenesin 100mg, menthol 1mg, per 5ml)

   100ml Syr.      

 

Indoco

EFFLIN                              

Tab: Salbutamol 2mg, etophyllin 200mg, bromhexine 8mg/5ml)

   10 Tab               

 

PD: Syr.  (Salbutamol 1mg, bromhexine HCl 2mg, guaiphesin 50mg, menthol 0.5mg/5ml)

   100ml Syr       

 

Khandelwal

EXIPLON-BR                

(Salbutamol sulphate 1mg, bromhexine HCl 2mg, Guaiaphenesin 50mg, menthol  0.5mg/5ml)

   50ml syr.      

   100ml syr.       

 

SALMAPLON  

   10 Tab                    2mg    

                                4mg   

 

Aglow med

INSTARYL                   

(Salbutamol 2mg, bromhexine HCl 4mg, Phenylephrine HCl 2.5mg, per 5ml)

   100ml Syr.       

 

INSTARYL-P  

(Salbutamol 1mg, Ambroxol 15mg, Guaiaphenesin 50mg, menthol 5mg, per 5ml)

   100ml Syr.      

 

Tridoss

PEDEX-S                         

(Salbutamol 2mg, bromhexine HCl 2mg, Guaiaphenesin 50mg, menthol 0.5mg, per 5ml)

   100ml Syr    

 

Stadmed

PULMO-REST    (Salbutamol 2mg, bromhexine HCl 8mg)

   10 Tab           

 

FDC

 

SALBETOL                             

   10 Tab                    2mg    

                                4mg      

 

SALMODIL EXP  (Salbutamol (as sulph) 2mg, bromhexine HCl 4mg/5ml)

   110ml Syr.     

 

Eros Pharma

SALBID                        

   (10x5x10) Tab       2mg    

4mg 

   10x10 Tab Retard  4mg   

8mg   

 

SALBID EXP (Salbutamol 2mg, bromhexine HCl 8mg, per 10ml)

   120ml Syr.    

 

Albert David

 

SIOKOF AS   (Salbutamol 1mg, Ambroxol HCl 15mg, per 5ml)

   100ml syr.        

 

Bio-Drug

SPASMONYL                

(Salbutamol sulphate 2mg, bromhexine HCl 4mg, Guaiaphenesin 50mg, menthol 0.5mg, per 5ml)

   100ml Syr.       

   450ml Syr.        

 

Comed

 

SUDEX BR EX.   (Salbutamol 1mg, bromhexine HCl 2mg, Guaiaphenesin 50mg, menthol 0.5mg, per 5ml)

         100ml Syr.     

 

Concept

 

SYNABRON EXP   (Salbutamol 2mg, bromhexine 8mg, Guaiaphenesin 100mg)

   10 Tab      

 

Mapra Labs

VENTILATE                 

Salbutamol (as sulphate) 2mg, Bromhexine HCl 8mg, each tab or 5ml Syrup)

   10 Tab             

   100ml Syr.     

Forte Tab: Salbutamol 4mg, Bromhexine HCl 16mg)

 

Mount Mettur

 

VENTIL-B FORTE   (Salbutamol 4mg, Bromhexine 8mg)

   10 Tab F       

 

Unimarck

VENITIREX PLUS   (Salbutamol 2mg, theophylline 100mg)

   10 Tab        

 

Syr.: (Salbutamol 1mg, choline theophyllinate 50mg, per 5ml)

   100ml Syr.